Psychology 675

Clinical Research Methods

Fall 2004

 

Lizabeth Roemer, Ph.D.

Lizabeth.Roemer@umb.edu

M-4-215/7-6358

Office hours T Th 11:30 – 1pm

 

Course description: The goal of this course is to provide you with the expertise necessary (a) to evaluate the adequacy of published research and to draw your own conclusions from existing empirical findings, (b) to generate logical, novel hypotheses based on theories and prior empirical results about psychopathology and psychotherapy, and (c) to create valid experimental designs and methodologies to test those hypotheses.

 

Evaluation:

Critical reviews of articles (10% each)  At three points during the semester you will be asked to submit an article and a critical review of that article. You will focus on the particular issues we are covering in class during that time. Thus the first critique will focus on hypothesis development and issues of internal and external validity, the second will focus on issues in treatment outcome studies, and for the final critique you will address cultural issues. Each critique should contain suggestions for future research as well (at least one concrete suggestion of how this area of research can be continued). You should consult with your mentors and try to choose articles relevant to your area of research interest. Critiques will be evaluated based on application of critical thinking and concepts learned in class – comprehensive critiques are not expected. A good critique is able to link weaknesses in design with limitations to conclusions drawn and discusses what conclusions can be drawn given various flaws, as well as which conclusions cannot be made due to the design.        Due dates: 9/29, 10/18, 11/22

 

Two exams (15% each). These will be in class, straightforward examinations that assess your comprehension and recall of central concepts in research design. They will be drawn largely from course readings. These exams are included to ensure that you truly master the core concepts of research methodology so that you can use them effortlessly as both a researcher and consumer of empirical studies.          Dates:  10/25 & 12/1

 

Final research proposal (optional and ungraded) You may choose to turn in a draft of your masters research proposal that includes specific aims, background and significance, and research design. Hopefully, this can serve as your first draft of your master’s proposal. However, you may not have finalized your project yet, in which case this can serve as practice in writing up a research proposal in the area you are interested. You should work with me and with your mentor to settle on what to focus on if you have not finalized your research plan. This is an opportunity for you to receive methodological and conceptual feedback early in the process of formulating your Master’s thesis. However, if writing something up at this point is too stressful, you are free to choose not to do this assignment at all. However, everyone must do the presentation described below.

Due date: 12/20

 

Research Proposal Presentation (10%) The last three class periods will be devoted to informal presentations of your Masters’ thesis ideas. You will each have about 20 minutes to talk about your research. Feel free to use this time to solicit suggestions regarding problematic aspects of your research design - you will have the benefit of 8 other newly trained research methodologists to help you problem-solve.           Due date: 12/6, 12/8, & 12/13

 

Class participation and preparation (30%) I expect you to come to class having read the assigned readings and thought about them. I will provide questions to help you think about your own research in relation to the readings, and you will also be given empirical articles that demonstrate methodological points we are discussing that you should be prepared to critique in class. You do not need to turn in formal answers to these questions, but you should bring notes so you are prepared to discuss them in class. In addition, if any questions arise while you are doing the reading, I would appreciate an email by 10am the day the reading is due just telling me what you would like me to talk about in class.  I will use these notes to structure class – they will help me determine what areas I should particularly focused on. You do not have to send me an email; this suggestion is not meant to make more work for you. It is just a way for me to make sure that I address everyone’s questions during class time and it gives me a little bit of time to look up anything that someone wonders about that I don’t already know.

 

Required textbook:

 

Kazdin, A.E. (2002). Research design in clinical psychology (4th ed.) Boston: Allyn & Bacon.

 

Tentative schedule of readings and topics to be covered

 

9/8  Introduction, why do we need to understand clinical research?

 

9/13  Building a research idea

 

Kazdin Ch.1, Ch 5

Platt, J.R. (1964). Strong inference. Science, 146, 347-353.

 

9/15  Building a research idea continued

 

turn in one page summary of research thoughts for masters

 

9/20   Drawing valid inferences I

 

Kazdin Chapter 2

Kazdin, A.E. (1978). Evaluating the generality of findings in analogue therapy research. Journal

of Consulting and Clinical Psychology, 46, 673-686.

Borkovec, T.D. & Rachman, S. (1979). The utility of analogue research. Behaviour Research

and Therapy, 17, 253-261.

 


9/22 Drawing valid inferences II

 

Kazdin Chapters 3 & 4

Roemer, L., & Borkovec, T. D. (1994). Effects of suppressing thoughts about emotional

material.  Journal of Abnormal Psychology, 103, 467-474.

      come to class prepared to critique based on the readings of the week

 

9/27   Experimental design

 

Kazdin chapters 6 & 8

 

9/29 Experimental design 2

 

van de Vijver & Leung chapter 2

Baron, R.M., & Kenny, D.A. (1986). The moderator-mediator variable distinction in social

psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173-1182. 

Kraemer, H. C., Stice, E., Kazdin, A., Offord, D., & Kupfer, D. (2001). How do risk factors work together? Mediators, moderators and independent, overlapping, and proxy risk factors. American Journal of Psychiatry, 158, 848-856.

critique #1 due

 

Think about: what type of design are you thinking of using for your masters - how do this week’s

readings relate?         

 

10/4    Dependent variables

 

Kazdin chapter 13

Nisbett & Wilson (1977). Telling more than we can know: Verbal reports on mental processes.

Psychological Review, 84. 231-259.

Think about: What measurement issues are you struggling with for your masters project?

 

10/6 Control groups/psychotherapy research

 

Kazdin Chapters 7 & 14

Borkovec, T.D. (1994). Between-group therapy outcome research: Design and methodology. In

L.S. Onken & J. D. Blaine (Eds.), NIDA Research Monograph #137, pp. 249-289. Rockville, MD:  National Institute of Drug Abuse.

Castonguay, L.G.  (1993). Common factors" and "nonspecific variables": Clarification of the

two concepts and recommendations for research. Journal of Psychotherapy Integration, 3, 267-286.

 


10/11    Empirically supported treatments

 

Chambless, D.L., & Hollon, S.D. (1998). Defining empirically supported therapies. Journal of

Consulting and Clinical Psychology, 66, 7-18

Borkovec, T.D., & Castonguay, L.G. (1998) What is the scientific meaning of empirically

supported therapy? Journal of Consulting and Clinical Psychology, 66, 136-142.

Goldfried, M.R., & Wolfe, B.E. (1998) Toward a more clinically valid approach to therapy

research. Journal of Consulting and Clinical Psychology, 66, 143-150.

Jacobson, N.S., Roberts, L. J., Berns, S. B., & McGinchey, J. B. (1999). Methods for defining

and determining the clinical significance of treatment effects: Description, application, and alternatives. Journal of Consulting and Clinical Psychology, 67, 300-307.

Gladis, M. M., Gosch, E. A., Dishuk, N. M.  & Crits-Cristoph, P. (1999). Quality of life:

Expanding the scope of clinical significance. Journal of Consulting and Clinical Psychology, 6, 320-331.

Rounsaville, B. J., Carroll, K. M., & Onken, L. S. (2001). A stage model of behavioral therapies

research: Getting started and moving on from Stage I. Clinical Psychology: Science and

Practice, 8, 133-142.

 

10/13  More on empirically supported treatments

 

Westen, D., Novotny, C.M., Thompson-Brenner, H. (2004). The empirical status of empirically supported psychotherapies: assumptions, findings, and reporting in controlled clinical trials. Psychological Bulletin, 130, 631-663.

 

Haaga, D.A.F. (2004). A healthy dose of criticism for randomized trials: Comment on Westen, Novotny, and Thompson-Brenner (2004). Psychological Bulletin, 130, 674-676.

 

Westen, D. Novotny, C. Thompson-Brenner, H. (2004). The next generation of psychotherapy research: Reply to Ablon and Marci (2004), Goldfried and Eubanks-Carter (2004), and Haaga (2004). Psychological Bulletin, 130, 677-683.

 

Crits-Christoph, P., Wilson, G. T., & Hollon, S.D. (2005). Empirically supported psychotherapies: Comment on Westen, Novotny, and Thompson-Brenner (2005). Psychological Bulletin, 131, 412-417.

 

Rosen, G. M., & Davison, G. C. (2003). Psychology should list empirically supported principles of change (ESPs) and not credential trademarked therapies or other treatment packages. Behavior Modification, 27, 300-312.

 

Wilson, S.A., Becker, L.A. & Tinker, R.H. (1995). Eye movement desensitization and

reprocessing (EMDR) treatment for psychologically traumatized individuals. Journal of Consulting and Clinical Psychology, 63, 928-937. come to class prepared to critique based on readings

           

10/18  Research in clinical practice/Single case designs

 

Kazdin chapter 10 & 11

Borkovec, T.D., Echemendia, R.J., Ragusea, S.A., & Ruiz, M. (2001). The Pennsylvania Practice

Research Network and future possibilities for clinically meaningful and scientifically

rigorous psychotherapy effectiveness research. Clinical Psychology: Science and Practice, 8, 155-167.

Persons, J. B. (2001). Conducting effectiveness studies in the context of evidence-based clinical

practice. Clinical Psychology: Science and Practice, 8, 168-172.

 

critique #2 due

 

10/20 Case-control and Cohort Designs

 

Kazdin Chapter 9

 

10/25     EXAM #1

 

10/27 & 11/1   Cross-cultural research

van de Vijver & Leung Chapter 3

Excerpt from American Psychological Association (2003). Guidelines on multicultural education, training, research, practice, and organizational change for psychologists. American Psychologist, 58, 377-402.

Suzuki-Crumly, J. & Hyers, L. (2004) The relationship among ethnic identity, psychological well-being, and intergroup competence: An investigation of two biracial groups. Cultural Diversity and Mental Health, 10, 137-150. come to class prepared to critique based on readings

Walker, K. L., & Chestnut, D. (2003). The role of ethnocultural variables in response to terrorism. Cultural Diversity and Mental Health, 9, 251-262. come to class prepared to critique based on readings

 

Think about: How are you addressing cultural issues in your masters? Will your sample be ethnically diverse? How will you address this diversity? What questions will remain unanswered?

 

11/3 & 8   Qualitative research/process research

Kazdin chapter 12

Taylor, S. J. & Bogdan, R. (1998).  Introduction to qualitative methods: A guidebook and resource (3rd edition).  New York: Wiley & Sons.  Chapter 1 Introduction: Go to the People (pp. 3-23).

Chapter from Cresswell, J.W (2002). Research methods: Quantitative, Qualitative and Mixed Method Approaches.

Waldinger, R. J., Seidman, E.L., Gerber, A. J., Liem, J. H., Allen, J. P., & Hauser, S. T. (2003). Attachment and core relationship themes: Wishes for autonomy and closeness in the narratives of securely and insecurely attached adults. Psychotherapy Research, 13, 77-98. come to class prepared to critique based on readings

Thai, H.C. (1999). “Splitting things in half is so White!”: Conceptions of family life and friendship and the formation of ethnic identity among second generation Vietnamese Americans. Amerasia Journal, 25, 53-88. come to class prepared to critique based on readings

 

11/10 & 15 Statistical methods

Kazdin 15 & 16

 

Think about: What statistical methods are you likely to use in your masters? What questions do you have about them?

 

11/22

Ethics

Kazdin chapter 17

critique #3 due

 

11/29  Writing up results

Kazdin chapter 18

 

12/1  EXAM #2

 

12/6, 8 & 13                research proposal presentations